North Carolina Department of Motor Vehicles (License)

If you are relocating to North Carolina, you must obtain a N.C. driver's license within 30 days of establishing a permanent residence. If you drive a motorcycle you will need a motorcycle endorsement. Licensed drivers who are 16 or 17 years old must present proof of completion of a state-approved driver education course in their former state. If proof is not provided, they will receive a temporary license pending completion of the course here.
To receive a license, you must apply in person at a driver's license office and take the vision, sign recognition and written tests. (I recommend studying the "Driver's Handbook" available at DMV offices. Bring with you your current out-of-state license or two other accepted forms of ID and proof of liability insurance from an insurer licensed in North Carolina. You will also need to provide your Social Security number.

North Carolina Department of Motor Vehicles (Registration Requirements)

Vehicles must be registered before the reciprocity agreement between North Carolina and your former state expires. (usually 30 days) Registration is renewed annually. To register your vehicle, apply in person at a license plate agency with your title (unless title is held by a lienholder) and a valid registration card from your former state. If your title is held by a lienholder, you must provide the lienholder's name and address on a state form for title release. You also must present proof of liability insurance from an insurer licensed in N.C.  Fees that are due when you receive your N.C. registration include: Title fee, $35.00 registration fee, $20.00 and highway use tax, $40.00 to $150.00 depending on your particular vehicle. You also must get a vehicle inspection within 10 days of receiving your N.C. plates. This cost is $9.25 and can be done at any state-authorized inspection station. Inspections are required annually. In addition, if your car is licensed in Mecklenburg or Cabarrus counties, you will also need an  emissions inspection which is conducted at the time of the vehicle inspection. The cost is $19.40.